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SARS-CoV-2 Mutations – Cause for Concern? (Revised 1)

SARS-CoV-2 Mutations – Cause for Concern? The accumulation of genetic mutations is a normal part of viral evolution. Mutations change the sequence of the viral genome, creating different ‘variants.’ While some mutations might be silent, with no visible clinical effect, others might have implications for disease transmission, severity, reinfection potential, and immunity. SARS-CoV-2 variants A recently described clinically significant mutation has been termed N501Y, which put simply means that the amino acid ‘N’ at position 501 of the spike protein has [...]

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Why No Two Products Are Equal…

In this blog, we take a look at technical design problems with primer/probes if not designed to the standard required. The design process is a pivotal part of the process in the manufacturing of primer/probe that will enable it to function as well as possible. Good primer design is vital in providing a successful PCR reaction and to ensure quantitative, accurate and interpretable results in your qPCR testing. There are many factors and to take into account when designing the [...]

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